Phase 2 trial of bintrafusp alfa as second-line therapy for patients with locally advanced/metastatic biliary tract cancers.

Changhoon Yoo,Milind M Javle, Helena Verdaguer Mata,Filippo de Braud,Jörg Trojan,Jean-Luc Raoul,Jin Won Kim,Makoto Ueno,Choong-Kun Lee,Susumu Hijioka, Antonio Cubillo,Junji Furuse,Nilofer Azad,Masashi Sato,Yulia Vugmeyster,Andreas Machl,Marcis Bajars,John Bridgewater,Do-Youn Oh,Mitesh J Borad

Hepatology (Baltimore, Md.)（2023）

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摘要

Although this study did not meet its prespecified primary endpoint, bintrafusp alfa demonstrated clinical activity as second-line treatment in this hard-to-treat cancer, with durable responses and a manageable safety profile.

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关键词

advanced/metastatic biliary tract cancers,bintrafusp alfa,biliary tract,second-line

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