A longitudinal analysis of humoral, T cellular response and influencing factors in a cohort of healthcare workers: Implications for personalized SARS-CoV-2 vaccination strategies.

Eleonora Sabetta,Maddalena Noviello,Clara Sciorati,Marco Viganò,Rebecca De Lorenzo,Valeria Beretta,Veronica Valtolina,Chiara Di Resta,Giuseppe Banfi,Davide Ferrari,Massimo Locatelli,Fabio Ciceri,Chiara Bonini,Patrizia Rovere-Querini,Rossella Tomaiuolo

Frontiers in immunology（2023）

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摘要

These findings suggest prospects for rescheduling vaccination strategies by considering individual immunization status, personal characteristics, and the appropriate laboratory tests to portray immunity against SARS-CoV-2 accurately. Deepening our knowledge about T and B cell dynamics might optimize the decision-making process in vaccination campaigns, tailoring it to each specific immune response.

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COVID-19,SARS-CoV-2 vaccination,T-cell response,influencing factors (variables),serological tests and risk factors

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