Adenosine 2A receptor contributes to the facilitation of post-infectious irritable bowel syndrome by γδ T cells via the PKA/CREB/NF-κB signaling pathway.

Li-Wei Dong,Yi-Yao Chen,Chao-Chao Chen,Zhi-Chao Ma,Jiao Fu,Bai-Li Huang,Fu-Jin Liu,Dong-Chun Liang,De-Ming Sun,Cheng Lan

World journal of gastroenterology（2023）

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摘要

Our results revealed that A2AR contributes to the facilitation of PI-IBS by regulating the function of γδ T cells the PKA/CREB/NF-κB signaling pathway.

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关键词

Adenosine 2A receptor,Irritable bowel syndrome,Post-infectious irritable bowel syndrome,Regulation,Signaling pathway,γδ T cells

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