Interleukin-6 trans-signaling induced laminin switch contributes to reduced trans-endothelial migration of granulocytic cells.

Mulugeta M Zegeye,Ljubica Matic,Mariette Lengquist, Assim Hayderi,Magnus Grenegård,Ulf Hedin,Allan Sirsjö,Liza U Ljungberg,Ashok K Kumawat

Atherosclerosis（2023）

引用 2|浏览3

暂无评分

摘要

We showed that expression of endothelial laminin alpha chains is regulated by IL-6 trans-signaling and contributes to inhibition of trans-endothelial migration of granulocytic cells. Further, expression of laminin alpha chains is altered in human atherosclerotic plaques and is related to intra-plaque abundance of leukocyte subpopulations.

查看译文

关键词

Atherosclerosis,Chronic inflammation,Diapedesis,Endothelial basement membrane,Plaque stability

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要