Supplemental Figure S5 from Treatment-Induced Tumor Cell Apoptosis and Secondary Necrosis Drive Tumor Progression in the Residual Tumor Microenvironment through MerTK and IDO1

Supplemental Figure S5. Decreased tumor cellularity of tumors treated with the combination of lapatinib + BMS-777607 + epacadostat. Low power images of H&E-stained sections of tumors collected at treatment day 7. Arrows point to tumor cells, which stain darker purple, and which are evident as solid sheets in vehicle-treated samples, but only as pockets in the samples treated with lapatinib + BMS-777607 + Epacadostat. Asterisks represent areas of acellular debris.