Table S4, Table S5, Table S6 from Transcriptomic Differences between Primary Colorectal Adenocarcinomas and Distant Metastases Reveal Metastatic Colorectal Cancer Subtypes

Table S4. Pathway enrichment differences between CRC primary tumors and metastases (liver and lung) without appropriate adjustment of treatment exposure status in the MCC and Consortium datasets in the tissue sensitive setting: Hallmark and C2 Collections. Table S5. Pathway enrichment differences between treatment naïve and treatment exposed CRC tumors in the MCC and Consortium datasets, while adjusting for tumor type (primary or metastasis) status in the tissue sensitive setting: Hallmark and C2 Collections. Table S6. Comparison of treatment exposed (post treatment) and treatment naïve (pre treatment) metastases in the MCC dataset. Here, the up direction refers to treatment exposed metastases, while down refers to treatment naïve metastases. Pathways are from the Hallmark and C2 Collections. All FDR values shown are <0.1.