Supplemental Figures 1 - 4 from Idelalisib Impacts Cell Growth through Inhibiting Translation-Regulatory Mechanisms in Mantle Cell Lymphoma

Supplemental Figure 1. Effect of idelalisib on the cell cycle in MCL cell lines and primary cells. Supplemental Figure 2. Effect of idelalisib treatment on the AKT/mTOR-mediated translation regulation pathway in MCL cell lines. Supplemental Figure 3. Relationship of protein synthesis inhibition with growth inhibition and decrease of protein phosphorylation targets by idelalisib treatment in MCL lines and primary cells. Supplemental Figure 4. Composite immunoblot panels for MCL cell lines and primary cells to explain use of loading control in different figures.