Supplementary Figure 6 from The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas Beatrice Gini , Ciro Zanca , Deliang Guo , Tomoo Matsutani , Kenta Masui , Shiro Ikegami , Huijun Yang , David Nathanson , Genaro R. Villa , David Shackelford , Shaojun Zhu , Kazuhiro Tanaka , Ivan Babic , David Akhavan , Kelly Lin , Alvaro Assuncao , Yuchao Gu , Bruno Bonetti , Deborah S. Mortensen , Shuichan Xu , Heather K. Raymon , Webster K. Cavenee , Frank B. Furnari , C. David James , Guido Kroemer , James R. Heath , Kristen Hege , Rajesh Chopra , Timothy F. Cloughesy , Paul S. Mischel crossref(2023)
摘要
PDF file - 2561K, Treatment with CC214-1, leads to induction of autophagy in GBM39 cells and genetic inhibition of autophagy sensitizes U87EGFRvIII cells to apoptosis.
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