Disease identification method based on graph features between pulse cycles.

The pulse signal at the wrist communicates a range of cardiovascular information and reflects a person's state of health. In recent years pulse signals have been used extensively in the field of disease identification. As a typical quasi-cyclic physiological signal, many researchers have simply used single-cycle pulse signals for disease diagnosis, ignoring the influence of inter-cycle differences on the diagnosis. In this paper, we propose a disease identification method based on graph features between pulse cycles, to focus on the differences in pulse cycles brought about by the disease. The pulse was pre-processing using a Sliding Window, followed by the construction of the correlation coefficient matrix, the setting of a threshold and the construction of the connection graph to obtain the graph features; the Multiscale Permutation Entropy method was used to extract the pulse's entropy features. The ReliefF algorithm is then used to select a total of 18 features and a classification algorithm is used to distinguish between patients and healthy people. Both the self-constructed dataset and the open dataset from the PLA 211 Hospital had high recognition rates for the experiments. The accuracy of identifying hypertension was 94.16% with a precision of 90.41%; the accuracy of identifying chronic diseases was 97.23% with a precision of 97.81%. The experimental results from the two datasets demonstrate both the validity of the difference between cycles for disease classification and the applicability of the method proposed in this paper.