Integrated pan-cancer analysis and experimental verification of the roles of tropomyosin 4 in gastric cancer.

Qijing Guo,Linglin Zhao, Nan Yan, Yan Li,Cuiping Guo, Shengyan Dang,Xianliang Shen, Jianfang Han,Yushuang Luo

Frontiers in immunology（2023）

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摘要

TPM4 is a prospective marker for the diagnosis, treatment outcome, immunology, chemotherapy, and small molecular drugs targeted for pan-cancer treatment, including GC treatment. The lncRNA-miRNA-TPM4network regulates the mechanism underlying GC progression. TPM4 may facilitate the invasion and migration of GC cells, possibly through ECM remodeling.

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关键词

experiment,gastric cancer,immune infiltrating,integrative analysis,pan-cancer,tropomyosin 4

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