Fibrinogen-like protein 1 promotes liver-resident memory T-cell exhaustion in hepatocellular carcinoma.

Frontiers in immunology（2023）

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摘要

We identified CD8T cells as a potential immunotherapeutic target and reported the effect of FGL1-LAG3 binding on CD8 T cell function in HCC.

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关键词

exhaustion,granzyme B,hepatocellular carcinoma,lymphocyte activation gene 3,tissue-resident memory T cells

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