Supplementary Figure 4 from Fibroblast-Derived Dermal Matrix Drives Development of Aggressive Cutaneous Squamous Cell Carcinoma in Patients with Recessive Dystrophic Epidermolysis Bullosa

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PDF file - 79K, A: Average array signal intensities �SD for the single probe representing COL7A1, n=3-5. B: Western blotting shows the level of type VII collagen varies between sample groups, increased in both UVSCCF samples compared with NHF. Type VII collagen is identified in RDEB fibroblast samples from patients with the following COL7A1 genotypes: x79 6501G>A/unknown and 2470insG/2470insG, and RDEBSCC fibroblasts samples from patients with x31 3832-1G>A/Unknown and x73 6075delC/unknown COL7A1 genotype.

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