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Figures S1-S6 from SKP2 Activation by Thyroid Hormone Receptor β2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells

crossref(2023)

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摘要

Figure S1. TRβ2 and TRβ1 inversely regulate retinoblastoma cell proliferation and cell cycle progression.Figure S2. Pituitary anterior lobe and intermediate lobe markers and Trβ isoforms expressed in pituitary tumors in Rb1+/- mice of different Trβ genetic backgrounds.Figure S3. EMI1 mediates TRβ2 regulation of SKP2.Figure S4. Rescue of Rb knockdown-induced cell cycle arrest and SKP2 down-regulation by ectopic Rb expression.Figure S5. Gene expression changes in response to RB1-KD in synchronized SKN-BE(2) neuroblastoma cells.Figure S6. TRβ1 and TRβ2 regulate proliferation and SKP2 and p27 expression in Rb-deficient MXF8000 myxofibrosarcoma cells.

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