Supplementary Figures and Figure Legends and Table from Integrin αvβ3 and Fibronectin Upregulate Slug in Cancer Cells to Promote Clot Invasion and Metastasis

PDF file, 893K, Supplementary table, figures, figure legends and methods Files in this Data Supplement: � Supplementary Movie 1 - WMV file, 12420 K. Live cell imaging (phase contrast, 10x) of 786-0 cells over 72 hours after embedding in fibrin. � Supplementary Movie 2 - WMV file, 11607 K. Live cell imaging (phase contrast, 10x) of MDA-MB-231 cells over 72 hours after embedding in fibrin. � Supplementary Table, Figures and Legends - PDF file, 893 K. Supplementary Table 1: Clinicopathological data of patients with RCC. Figure S1A: Colony formation of 786-0 and MDA-MB-231 cells. Figure S1B: Cell surface expression of integrin �v�3 analyzed by flow cytometry. Figure S2: Effect of integrin �1 and �3 knockdown. Figure S3: Tumor cell spreading on fibrinogen-coated surface. Figure S4: Effect of fibronectin knockdown. Figure S5: Effect of Slug knockdown or inhibition with the TGF-�RII inhibitor SB431542 (EMD Millipore).