A catechol-containing dialdehyde cellulose adhesive with strong adhesion and biocompatibility

Adhesives can connect two or more materials together through interfacial adhesion and cohesion, which have wide range applications in the fields of wood, packaging and biomedicine. Currently, environmentally-friendly bio-based adhesives are considered to be a good alternative to non-renewable petroleum-based adhesives. In this paper, a catechol-containing dialdehyde carboxymethyl cellulose (DCMC-DA) adhesive with strong adhesion and biocompatibility was reported. Carboxymethyl cellulose (CMC) was oxidized to dialdehyde carboxymethyl cel-lulose (DCMC) by oxidation reaction, then catechol groups were incorporated into DCMC to obtain DCMC-DA. The DCMC-DA was characterized by Fourier transform infrared and UV-Vis spectroscopy. The lap shear strength of DCMC-DA on porcine skin and wood were 0.14 MPa and 4.38 MPa, respectively, which increased by 350% and 694% as compared with that of CMC. Moreover, NIH 3T3 cell tests demonstrated that DCMC-DA has good biocompatibility to promote cell proliferation. The DCMC-DA with strong adhesion and biocompatibility has great potential as a green and environmentally friendly adhesive in the fields of wood and biomedicine.