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Challenging the Pleiotropic Effects of Repetitive Transcranial Magnetic Stimulation in Geriatric Depression: A Multimodal Case Series Study.

Vincenzo G Nicoletti,Francesco Fisicaro,Eugenio Aguglia,Rita Bella,Damiano Calcagno,Mariagiovanna Cantone,Carmen Concerto,Raffaele Ferri,Ludovico Mineo,Giovanni Pennisi,Riccardo Ricceri,Alessandro Rodolico,Giulia Saitta,Giulia Torrisi,Giuseppe Lanza,Manuela Pennisi

Biomedicines（2023）

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Abstract
We were unable to detect a relevant impact of high-frequency rTMS on mood, cognition, cortical microcircuits, neurotrophic/growth factors, and CBF. Cerebrovascular disease and exposure to multiple pharmacological treatments might have contributed.
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case series,cerebral hemodynamics,cortical excitability,mood disorders,neural plasticity,neuromodulation,neurotrophins,non-pharmacological interventions
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