乌司他丁在心脏外科围术期中的应用进展

Huang Shaojun,Liu Haiyuan,Zhang Shuaipeng,Wang Xiangyu,Wang Xinxin,Zhang Chengxin

wf（2023）

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Abstract

体外循环是心脏外科手术中不可或缺的组成部分,但由于其特殊的材质属性,在术中,患者体内的炎性因子、免疫机制等被异常活化,导致炎症反应的发生和加重,而蛋白酶抑制剂乌司他丁能够有效抑制炎性介质的释放和活化.本文就其药理机制、应用现状予以综述,旨在心外围术期内适当给药乌司他丁,对患者术后良性转归起到积极的临床意义.

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