IgG4 and IgE anti-Strongyloides stercoralis as additional parameters in characterizing patients with diabetes from a hyperendemic area.

Henrique T Gonzaga, Suzan Cristina L Mendonça,Ana Lúcia R Gonçalves,Álvaro Ferreira-Júnior,Rosângela Maria Rodrigues, Maria Do Rosário F Gonçalves-Pires,Nágilla D Feliciano, Vanessa da S Ribeiro,Julia Maria Costa-Cruz

Diagnostic microbiology and infectious disease(2023)

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摘要
We report the detection of IgG, IgG1, IgG4 and IgE anti-Strongyloides stercoralis as complementary tool for screening in patients with diabetes in hyperendemic areas for strongyloidiasis. A panel of 119 serum samples were analyzed: 76 from patients with DM2 and 43 patients with other endocrine diseases and a positive correlation for total IgG levels with IgG4 (rs = 0.559; P = 0.024; n = 16) and IgG and IgE (rs = 0.585; P < 0.0001; n = 76) was found in the diabetes group.
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关键词
Antibody profile,Endemic areas,Immunodiagnosis,Strongyloidiasis
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