Oxidation-sensitive Cysteines Drive IL-38 Amyloid Formation

Alejandro Diaz-Barreiro,Gea Cereghetti, Francisco Gabriel Ortega Sanchez,Jenna Tonacini,Dominique Talabot-Ayer,Sylvie Kieffer-Jaquinod,Vera Maria Kissling,Arnaud Huard,Christopher Swale,Tuomas P. J. Knowles,Yohann Coute,Matthias Peter,Antonio Frances-Monerris,Gaby Palmer

CELL REPORTS（2024）

Cited 0|Views24

Key words

IL-38,IL-1 cytokine family,redox switch,vicinal cysteines,disulfide bridges,protein aggregation,low complexity region,amyloid core,epidermis,unconventional secretion

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