Design and control of extraction combined with extractive distillation for separation isopropanol-butanol-ethanol-water with organic Rankine cycle

•The waste heat of extraction - extractive distillation is recovered by heat integration and organic Rankine cycles.•Compared with the heat-integrated process, organic Rankine cycle assisted process save 8.88% total annual cost.•The control scheme of organic Rankine cycle assisted extraction - extractive distillation process shows good robustness.