Early effect of bivalent human papillomavirus vaccination on cytology outcomes in cervical samples among young women in the Netherlands.

Tessa M Schurink-van 't Klooster,Albert G Siebers,Joske Hoes,Folkert J van Kemenade,Johannes Berkhof,Johannes A Bogaards,Hester E de Melker

Cancer medicine（2023）

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摘要

By linking nation-wide registries on pathology and vaccination, we show significant beneficial early effects of HPV-vaccination on LSIL, HSIL+, CIN3/AIS/carcinoma and hrHPV detection in young women upto 24 years of age who have a cervical sample taken before entry into the cervical cancer screening program.

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关键词

HSIL,LSIL,bivalent HPV-vaccine,cytological cervical abnormalities,high-grade cervical lesions,high-risk HPV,human papillomavirus,low-grade cervical lesions

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