Biofeedback Training to Increase PCO2 in Asthma with Elevated Anxiety: A One-Stop Treatment for Both Conditions?

For asthma patients with high anxiety, our brief training designed to raise PCO2 resulted in significant and sustained reductions in anxiety sensitivity and negative affect compared to slow-breathing training. The findings lend support for PCO2 as a potential physiological target for anxiety reduction in asthma.Trial Registration:clinicaltrials.gov Identifier: NCT00975273.