A Novel Strategy for Liposomal Drug Separation in Plasma by TiO 2 Microspheres and Application in Pharmacokinetics.

Yue-Yang Yu,Mei Yuan,Wei-Jie Qin,Hai-Hong Bai,Hong-Zhuo Liu,Jin-Jing Che

International journal of nanomedicine（2023）

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摘要

TiO extraction method was stable, reproducible, and reliable for quantitation of encapsulated docetaxel. Because of versatility of lipids, it is expected to a universal bioanalysis method for the pharmacokinetic study of liposomes.

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关键词

TiO2 microspheres,bioanalysis,coordinate binding,docetaxel liposomes,liposomal-encapsulated drug

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