The impact of immunosuppressive agents on immune checkpoint inhibitor efficacy in patients with advanced melanoma: A real-world, multicenter, retrospective study.

Shaked Lev-Ari,Michael Serzan,Tianmin Wu,Andrew Ip,Lauren Pascual,Brittany Sinclaire, Shari Adams, Michael Marafelias,Lakshmi Ayyagari,Sarvarinder K Gill,Barbara Ma,Jacob P Zaemes,Alexandra Della Pia,Adil Alaoui,Subha Madhavan,Anas Belouali,Andrew Pecora,Jaeil Ahn,Michael B Atkins,Neil J Shah

Cancer（2023）

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摘要

These findings in patients with melanoma who were treated with ICIs suggest that the use of SSs or ISAs for the management of irAEs is not associated with inferior disease outcomes, which supports the use of these agents when necessary.

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关键词

immune checkpoint inhibitors,immune-related adverse events,immunosuppressive agents,melanoma,nivolumab,pembrolizumab,steroids

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