Extracellular matrix collagen biomarker levels in patients who underwent pulmonary endarterectomy.

Ahmet Zengin,Rabia Kalkan, Kübra Yıldız Aydın,Şehnaz Olgun Yıldızeli,BüLent Mutlu,Ayşe Zehra Karakoç,Serpil Taş,Hasan Sunar,Ülkan Kılıç,Mehmed Yanartaş,Bedrettin Yıldızeli

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery（2023）

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摘要

This study indicates that serum levels of extracellular matrix collagen biomarkers were similar in patients with CTETH who were candidates for surgery and in patients who had non-pulmonary hypertension who underwent lung surgery. Differences in levels of MMP-9/ß-actin in tissue samples may play a role in pulmonary vascular remodelling in operable patients.

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关键词

chronic thromboembolic pulmonary hypertension,matrix metalloproteinases 2 and 9,pulmonary endarterectomy

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