LRRC8A anion channels modulate vasodilation via association with Myosin Phosphatase Rho Interacting Protein (MPRIP).

Hyehun Choi,Michael R Miller, Hong-Ngan Nguyen, Jeffrey C Rohrbough, Stephen R Koch,Naoko Boatwright,Michael T Yarboro,Rajan Sah,W Hayes McDonald,J Jeffrey Reese,Ryan J Stark,Fred S Lamb

bioRxiv : the preprint server for biology（2023）

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摘要

Interaction of Nox1/LRRC8A with MPRIP/RhoA/MYPT1/actin may allow redox regulation of the cytoskeleton and link Nox1 activation to both inflammation and vascular contractility.

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