Mendelian randomization study of diabetes and dementia in the Million Veteran Program.

Elizabeth M Litkowski,Mark W Logue, Rui Zhang,Brian R Charest,Ethan M Lange,John E Hokanson,Julie A Lynch,Marijana Vujkovic,Lawrence S Phillips,Richard L Hauger,Leslie A Lange,Sridharan Raghavan

medRxiv : the preprint server for health sciences（2023）

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摘要

We found evidence of causality between diabetes and dementia using a one-sample MR study, with access to individual level data, overcoming limitations of prior studies utilizing two-sample MR techniques.

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