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Implementing New Approach Methodologies (nams) in Food Safety Assessments: Strategic Objectives and Actions Taken by the European Food Safety Authority

Irene Cattaneo, Maria Chiara Astuto, Marco Binaglia, Yann Devos, Jean Lou C. M. Dorne, Ana Fernandez Agudo, Antonio Fernandez Dumont, Pilar Garcia-Vello, George E. N. Kass, Anna Lanzoni, A. K. Djien Liem, Martina Panzarea, Konstantinos Paraskevopulos, Juan Manuel Parra Morte, Jose Tarazona, Andrea Terron

TRENDS IN FOOD SCIENCE & TECHNOLOGY（2023）

Cited 9|Views39
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Abstract
•NAMs, as alternatives to animal testing, have marginal use in regulatory assessments•Challenges and opportunities for including NAMs in food/feed safety assessments•Need for paradigm evolution and guidance to use non-apical effects in risk assessment•Opportunities for safety assessment of chemicals in food/feed, proteins and allergens•EFSA is paving the way for regulatory acceptance of non-standardized NAM-based results
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Key words
Animal-free testing,Preparedness,Risk assessment,Food,Feed,EFSA
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