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Precise tumor resection under the navigation of Tumor-Microenvironment pH-activated NIR-II fluorescence imaging via calcium Carbonate/Polydopamine Co-packed Nd-doped downshifting nanoprobes

Materials & Design(2023)

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摘要
•This DSNCs@hPCa-FA contrast nanoagent can specifically enhance tumor targeting capacity.•Robust NIR-II fluorescent imaging has been demonstrated to accurately identify tumor borderlines from normal tissue.•Tumors were thoroughly removed under the navigation of this novel pH stimuli-responsive NIR-II fluorescence imaging.
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关键词
Tumor microenvironment responsive,Down-shifting Nd-doped nanocrystals,NIR-II fluorescence imaging,Tumor surgery guidance
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