Adverse effects of systemic cancer therapy on skeletal muscle: myotoxicity comes out of the closet.

Pamela Klassen, Dalton L Schiessel,Vickie E Baracos

Current opinion in clinical nutrition and metabolic care（2023）

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摘要

The adverse side effect of cancer therapy on skeletal muscle has been largely ignored in the development of cancer therapeutics. Given the extent to which loss of muscle mass and function can bear on patients' function and quality of life, protection/mitigation of these side effects is a research priority.

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cancer, chemotherapy, immunotherapy, skeletal muscle atrophy, targeted therapy

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