The simultaneous action of acute paradoxical sleep deprivation and hypothyroidism modulates synaptosomal ATPases and acetylcholinesterase activities in rat brain.

Jasna Todorović,Marko Dinčić,Danijela Z Krstić,Mirjana B Čolović,Jelena Nešović Ostojić,Sanjin Kovačević,Srđan Lopičić,Svetolik Spasić,Predrag Brkić,Aleksandar Milovanović

Sleep medicine（2023）

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摘要

The effect of simultaneous existence of hypothyroidism and paradoxical sleep deprivation reduces the activity of the Na/K-ATPase, ecto-ATPases, and AChE, what is different from individual effect of hypothyroidism and paradoxical sleep deprivation itself. This knowledge could help in the choice of appropriate therapy in such condition.

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关键词

ATPases,Acetylcholinesterase,Hypothyroidism,Paradoxical sleep deprivation

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