Intrahepatic infiltration of activated CD8 + T cells and mononuclear phagocyte is associated with idiosyncratic drug-induced liver injury.

Hyun Yang,Ji Won Han,Jae Jun Lee,Ahlim Lee,Sung Woo Cho, Pu Reun Rho,Min-Woo Kang,Jeong Won Jang,Eun Sun Jung,Jong Young Choi,Pil Soo Sung,Si Hyun Bae

Frontiers in immunology（2023）

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摘要

Activated CD8+ T cells and mononuclear phagocyte are associated with liver injury caused by drugs. Therefore, we suggest that steroids are a potential treatment option for idiosyncratic DILI.

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关键词

T cell,drug-induced liver injury,flow cytometry,mononuclear phagocyte,steroid

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