Liver-stage Plasmodium infection tunes clinical outcomes.
Trends in parasitology(2023)
摘要
Chora and colleagues show that infection of the liver by Plasmodium modulates severity of disease in the experimental cerebral malaria (ECM) model by generating gamma delta (ɣδ) T cells that produce IL-17. This work calls into question the long-standing assumption that liver infection does not modulate severity of malaria.
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