Total flavonoids of Polygala fallax Hemsl induce apoptosis of human ectopic endometrial stromal cells through PI3K/AKT/Bcl-2 signaling pathway.

Chuanmei Zhong,Gongchenhao Ju,Sufang Yang,Xiangpei Zhao,Jixiang Chen,Ning Li

Gynecologic and obstetric investigation（2023）

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Abstract

PFHF reduce the expression of PI3K, AKT, Bcl-2 and Bcl-xl through the PI3K/AKT/Bcl-2 signaling pathway to inhibit HEcESCs proliferation, migration, and invasion and promote their apoptosis.

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