Peripheral lymphocyte fluctuation as an indicator of severe immune-related adverse events in patients treated with immune checkpoint inhibitors.

Masafumi Haraguchi,Yasuhiko Nakao,Syouhei Narita,Kousuke Matsumoto,Masanori Fukushima,Ryu Sasaki,Takuya Honda,Satoshi Miuma,Hisamitsu Miyaaki,Kazuhiko Nakao

Cancer medicine（2023）

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摘要

The percentage change in lymphocyte count was found to correlate with the incidence of severe irAEs. Close monitoring of the patient's condition is crucial when the lymphocyte count decreases during ICI treatment.

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关键词

CTLA-4 inhibitors,irAEs,liver injury,neutrophil-lymphocyte ratio

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