Association between endocrine therapy and cognitive decline in older women with early breast cancer: Findings from the prospective CLIMB study.

Joosje C Baltussen,Marloes G M Derks,Annelieke A Lemij,Nienke A de Glas,Marta Fiocco,Eugenie M H Linthorst-Niers,Annelie J E Vulink,Leander van Gerven,Onno R Guicherit,Thijs van Dalen,Jos W S Merkus,Titia E Lans,Carmen C van der Pol,Simon P Mooijaart,Johanneke E A Portielje,Gerrit-Jan Liefers

European journal of cancer (Oxford, England : 1990)（2023）

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摘要

Cognition of older women with early breast cancer did not decline in the first two years after treatment initiation, irrespective of ET. Our findings suggest that the fear of declining cognition does not justify the de-escalation of breast cancer treatment in older women.

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关键词

Breast cancer,Cognition,Endocrine therapy,Longitudinal,MMSE,Older women

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