Psychometric approaches to defining cognitive phenotypes in the Old Order Amish.

Andrew Zaman,Laura Caywood,Michael Prough,Jason Clouse, Sharlene Harrington,Larry Adams,Denise Fuzzell,Sarada Fuzzell,Renee Laux,Sherri D Hochstetler,Paula Ogrocki,Alan Lerner,Jeffery M Vance,Jonathan L Haines,William K Scott,Margaret A Pericak-Vance,Michael L Cuccaro

International journal of geriatric psychiatry（2023）

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摘要

Memory cluster stratification identified the cognitive phenotypes that best aligned with clinical classifications, APOE-e4, and cognitive performance We predict these phenotypes will prove useful in searching for protective genetic variants.

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关键词

Alzheimer's,Amish,cluster,cognition,phenotype,psychometric

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