Brain malformations in diprosopia observed in clinical cases, museum specimens and artistic representations.

Helga Rehder,Susanne G Kircher,Katharina Schoner,Mateja Smogavec,Jana Behunova, Ulrike Ihm,Margit Plassmann, Manuel Hofer,Helmut Ringl,Franco Laccone

Orphanet journal of rare diseases（2023）

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摘要

Brain malformations in patients with diprosopus may not be regarded as an independent event but rather as a sequel closely related to the duplication of the notochord and neural plate and as a consequence of the cerebral and associated craniospinal structural instabilities.

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关键词

CNS malformations,Cerebral di-symmetry,Diprosopus,Holoprosencephaly,ICSI,Janiceps,Parasitic twin,Paul Klee,Schedels world chronicle,Tlatilco culture

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