A Novel Construct of Coral Granules-Poly-L-Lactic Acid Nanomembrane Sandwich Double Stem Cell Sheet Transplantation as Regenerative Therapy of Bone Defect Model.

Gehan Abd-Elfatah Tawfeek,Mostafa Abdelgaber, Shaaban Gadallah,Anis Anis,Ahmed Sharshar

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation（2023）

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摘要

Poly-L-lactic acid nanofiber has greater osteogenic differentiating effect than the coral granules. The new approach of sDCS-PLLA-coral construct proved success for bone regeneration and repairing the bone gap and this may improve the design of tissue constructs for bone tissue regenerative therapy.

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关键词

Bone tissue regeneration,Human Wharton jelly mesenchymal stem cells,Nanofiber scaffolds,Sandwich double stem cell sheet

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