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Incidence and Prognosis of COVID-19 in Patients with Psoriasis: A Multicenter Prospective Study from the Eastern Black Sea Region of Turkey

Leyla Baykal Selcuk,Burak Aksan, Sevgi Kulakli,Isil Deniz Oguz, Mustafa Gundogdu, Gokturk Dere, Sevda Onder, Fatma Etgu, Deniz Aksu Arica, Seyda Ece Oguzer, Burcu Aydemir, Ibrahim Etem Arica, Yunus Saral,Savas Yayli

Acta dermatovenerologica Croatica : ADC(2022)

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Abstract
COVID-19 infection can have a poor prognosis, especial-ly in patients with chronic diseases and those receiving immunosup-pressive or immunomodulating therapies.This study aimed to investigate the severity of COVID-19 infection in patients with psoriasis and compare the infection severity for sys-temic treatments and comorbidities.We conducted a study in the dermatology clinics of five different centers in the Eastern Black Sea region of Turkey. Four hundred and eighty-eight patients were included, and 22.5% were confirmed as having COVID-19 infection.In our study, the frequency of hospitalization rates due to COVID-19 infection were similar (15.4%, 25.9% respectively) in patients receiv-ing biological treatment and receiving non-biological systemic treat-ment (P=0.344). Hospitalization rates were higher in patients with hypertension, androgenetic alopecia, and acitretin use (P=0.043, P=0.028, P=0.040).In conclusion, current biologic treatments and non-biologic system-ic treatments in patients with psoriasis did not appear to increase the risk of the severe form of COVID-19, except for acitretin.
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Key words
COVID-19,psoriasis,comorbidity,biologic,non-bio-logic systemic drugs
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