The challenges of selective fertility and carryover effects in within-sibship analyses: the effect of assisted reproductive technology on perinatal mortality as an example.

Kjersti Westvik-Johari,Siri E Håberg,Deborah A Lawlor,Liv Bente Romundstad,Christina Bergh,Ulla-Britt Wennerholm,Mika Gissler,Anna-Karina A Henningsen,Aila Tiitinen,Anja Pinborg,Signe Opdahl

International journal of epidemiology（2023）

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摘要

Whereas population estimates may be biased by residual confounding, within-sibship estimates were biased by selective fertility and carryover effects. It remains unclear whether ART conception contributes to perinatal mortality.

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关键词

Cohort study,assisted conception,carryover effects,continuation rate,perinatal death,perinatal mortality,selection bias,selective fertility,sibship design

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