Distinct disease mechanisms may underlie cognitive decline related to hearing loss in different age groups.

Jochum J van 't Hooft,Wiesje Pelkmans,Jori Tomassen,Cas Smits,Nienke Legdeur,Anouk den Braber,Frederik Barkhof,Bart van Berckel,Maqsood Yaqub,Philip Scheltens,Yolande Al Pijnenburg,Pieter Jelle Visser,Betty M Tijms

Journal of neurology, neurosurgery, and psychiatry（2023）

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摘要

Hearing loss was associated with amyloid binding in younger-old individuals only, and with cognitive decline in both age groups. These results suggest that mechanisms linking hearing loss with risk for dementia depends on age.

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关键词

ALZHEIMER'S DISEASE,AMYLOID,COGNITION,DEMENTIA

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