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Hepatitis B in Heart Transplant Donors and Recipients: A Systematic Review and Meta-Analysis.

Colin C Yost,Diana C Jimenez,Matthew P Weber,Elizabeth J Maynes,Katherine A Belden,Vakhtang Tchantchaleishvili,H Todd Massey,David A Sass,J Eduardo Rame,John J Zurlo,Nana Aburjania

The Journal of surgical research（2023）

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Abstract
Our review found that HBV D+/R- heart transplantation was associated with fewer active hepatitis infections and lower hepatitis-related mortality than D-/R+ transplantation, with comparable survival at 1 y. Additional studies utilizing HBV nucleic acid testing (NAT) to compare outcomes with HBsAg+ and anti-HBc+ donors are crucial to reach more definitive conclusions about the risk of donor-derived infections in this context.
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Key words
Donor pool expansion,Donor-derived infections,Heart transplantation,Hepatitis B
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