The role of Zn ions in the interaction between SARS-CoV-2 orf7a protein and BST2/tetherin

S. Botticelli,R. Chiaraluce,V. Consalvi,G. La Penna,A. Pasquo,M. Petrosino,O. Proux,G. C. Rossi,F. Stellato,S. Morante

European physical journal plus（2023）

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摘要

In this paper, we provide evidence that Zn ^2+ ions play a role in the SARS-CoV-2 virus strategy to escape the immune response mediated by the BST2-tetherin host protein. This conclusion is based on sequence analysis and molecular dynamics simulations as well as X-ray absorption experiments [ 1 ].

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关键词

zn ions,bst2/tetherin,protein,sars-cov

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