Altered glutamate-glutamine and amide proton transfer-weighted values in the hippocampus of patients with amnestic mild cognitive impairment: A novel combined imaging diagnostic marker.
Frontiers in neuroscience（2023）
Abstract
The combination of right hippocampal Glx levels and APTw values improved the diagnostic performance for aMCI, indicating it as a promising combined imaging diagnostic marker. Our study provided a potential imaging diagnostic strategy of aMCI, which may promote early detection of aMCI and facilitate timely intervention to delay the pathological progress toward AD.
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Key words
MEGA-PRESS,amide proton transfer-weighted imaging,amnestic mild cognitive impairment,hippocampus,imaging diagnostic marker
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