microRNA-627-5p inhibits colorectal cancer cell proliferation, migration and invasion by targeting Wnt2.

Dong-Yan Zhao,Teng-Fei Yin,Xi-Zhen Sun,Yuan-Chen Zhou,Qian-Qian Wang,Ge-Yujia Zhou,Shu-Kun Yao

World journal of gastrointestinal oncology（2023）

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摘要

miR-627-5p acts as a critical inhibitory factor in CRC, possibly by directly targeting Wnt2 and negatively modulating the Wnt/β-catenin signalling, revealing that miR-627-5p could be a possible treatment target for CRC.

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关键词

Colorectal cancer,Progression,Wnt2,miR-627-5p,β-catenin

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