Predictors of hepatitis C cure among people who inject drugs treated with directly observed therapy supported by peer case managers in Kenya.

Matthew J Akiyama,Lindsey R Riback,Mercy Nyakowa,Helgar Musyoki,John A Lizcano,Abbe Muller,Chenshu Zhang,Josephine G Walker,Jack Stone,Peter Vickerman,Peter Cherutich,Ann E Kurth

The International journal on drug policy（2023）

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Abstract

DOT with PCM-support was an effective model for HCV treatment among PWID in this LMIC setting. Adherence was the most important driver of SVR suggesting DOT and PCM support can overcome other factors that might limit adherence. Further research is necessary to ascertain the effectiveness of other models of HCV care for PWID in LMICs given NSP and MAT access is variable, and DOT may not be sustainable with limited resources.

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Key words

Africa,Direct-acting antivirals,Hepatitis c virus,Low- and middle-income countries,Peer,People who inject drugs

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