Weierning, a Chinese patent medicine, improves chronic atrophic gastritis with intestinal metaplasia.

Liping Han,Ting Li,Yingying Wang, Weizi Lai,Hengpu Zhou,Zhuangwei Niu,Jie Su,Guiyuan Lv,Guangji Zhang,Jianli Gao,Jianbo Huang,Zhaohuan Lou

Journal of ethnopharmacology（2023）

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摘要

This study demonstrated a positive effect of WEN on improving CAG and reverse intestinal metaplasia. These functions were related to the suppression of gastric mucosal cells' apoptosis and the inhibition of Hedgehog pathways' activation.

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关键词

Cdx2,Chronic atrophic gastritis,Hedgehog signaling pathway,Mitochondrial apoptosis,Muc2,Weierning

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