Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options.

International journal of molecular sciences(2023)

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摘要
is an opportunistic pathogen that mainly colonizes and infects cystic fibrosis patients' lungs. is naturally resistant to many antibiotics such as rifamycin, tetracyclines and β-lactams. The current therapeutic regimens are not very effective and are mostly based on repurposed drugs used against infections. Thus, new approaches and novel strategies are urgently needed. This review aims to provide an overview of the latest ongoing findings to fight infections by analyzing emerging and alternative treatments, novel drug delivery strategies, and innovative molecules.
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关键词
Mycobacterium abscessus,alternative strategies,antimicrobial peptides,antivirulence compounds,drug delivery,nitric oxide,phage therapy,phytochemicals
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