Effect of phosphodiesterase type 5 inhibitors on major adverse cardiovascular events and overall mortality in a large nationwide cohort of men with erectile dysfunction and cardiovascular risk factors: A retrospective, observational study based on healthcare claims and national death index data.
The journal of sexual medicine（2023）
Abstract
In a large population of US men with ED, PDE-5i exposure was associated with lower incidence of MACE, CV death, and overall mortality risk compared to non-exposure. Risk reduction correlated with PDE-5i exposure level.
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Key words
Erectile dysfunction,cardio-protection,major adverse cardiovascular events,myocardial infarction,phosphodiesterase inhibitors
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